Adjuvant Chemotherapy Combined With Targeted Therapy Versus Adjuvant Chemotherapy Alone in the Treatment of Stage T3-4N2 Colorectal Cancer:A Multicenter, Randomized, Phase III Clinical Trail
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 3
SUMMARY
The goal of this clinical trial\] is to compare in resectable stage T3-4N2 colorectal cancer. The main question it aims to answer is: whether the use of targeted therapy in combination with adjuvant chemotherapy is associated with improved disease-free survival (DFS) compared to adjuvant chemotherapy alone.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: f
View:
• Both sexes, aged 18-75 years;
• Pathologically confirmed pT3-4N2 stage colorectal adenocarcinoma after surgery;
• ASA grade \< IV and/or ECOG performance status score ≤ 2 points;
• Fully understand and voluntarily sign the informed consent form for this study.
Locations
Other Locations
China
The Sixth Affiliate Hospital of Sun Yat-Sen University
RECRUITING
Guangzhou
Time Frame
Start Date: 2023-04-01
Estimated Completion Date: 2033-04-01
Participants
Target number of participants: 366
Treatments
Experimental: Combining targeted therapy group
Adjuvant chemotherapy with targeted therapy
Sham_comparator: Single adjuvant chemotherapy group
Adjuvant chemotherapy alone
Related Therapeutic Areas
Sponsors
Leads: Sixth Affiliated Hospital, Sun Yat-sen University